Sino Biological has a professional mammalian cell expression platform with more than 10 years of process optimization and production experience, providing one-stop services from gene synthesis to high-quality antibody production. For the past 10 years, Sino Biological has successfully delivered thousands of recombinant antibodies manufacturing programs to customers worldwide and has established good cooperation relationships with leading pharmaceutical companies in the world. Sino Biological is the preferred antibody production service provider for Top10 pharmaceutical companies worldwide.
Sino Biological Inc. can achieve rapid and high-throughput recombinant antibody production. The preparation cycle is only 2-6 weeks, and the monomer purity can reach 99%.
Capacity and technology platform
|• >20 shakers, >800 bottles culture capacity weekly|
|• >100 bioreactors (2L~1000L)|
|• Cell culture capacity: >50,000 L yearly|
|• Free codon optimization|
|• Optimized high-efficiency expression vectors|
|• Optimized proprietary culture medium|
|• Optimized mammalian cell expression platform|
|• Experienced in expressing different kinds of antibodies:
scFv antibody, Fab antibody, full length antibody, chimeric antibody, bispecific antibody, multi-chains co-transfection and expression, etc.
|• Experienced in expressing and purifying multi-isotypes antibodies:
Human IgG1, IgG2, IgG3, IgG4
Mouse IgG1, IgG2a, IgG2b, IgG3
Rat IgG1, IgG2a, IgG2b, IgG2c
IgA, IgM, IgE
|• High monomer purity: up to 99%|
|• Low endotoxin level: as low as 0.1 EU/mg|
|• Comprehensive quality control analysis:
UV, SDS-PAGE, ELISA, qPCR, SEC-HPLC, CEX-HPLC, LC-MS/MS, CE-SDS, ADCC,CDC, OCTET Affinity, Kinetics, off-rate, ranking