MKK7 Protein Overview: Sequence, Structure, Function and Protein Interaction

MKK7 Protein Overview

MKK7 protein family

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

MKK7 protein name

Recommended name
Dual specificity mitogen-activated protein kinase kinase 7
Short name
MAP kinase kinase 7||MAPKK 7||MEK 7||SAPK kin
Jnkk2, MKK7
Alternative name
JNK-activating kinase 2 MAPK/ERK kinase 7 Stress-activated protein kinase kinase 4 c-Jun N-terminal kinase kinase 2

MKK7 Gene family protein

Mitogen-activated protein kinase kinases

MKK7 Protein Sequence

Species Human MKK7 protein
Length 419
Mass (Da) 47485
Sequence Human MKK7 protein sequence
Species Mouse MKK7 protein
Length 535
Mass (Da) 59312
Sequence Mouse MKK7 protein sequence
Species Rat MKK7 protein
Length 419
Mass (Da) 47536
Sequence Rat MKK7 protein sequence

MKK7 Protein Molecular Weight & PI

Dual specificity mitogen-activated protein kinase kinase 7 (EC (MAP kinase kinase 7) (MAPKK 7) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 2-419 Dual specificity mitogen-activated

Molecular weight (Da)


Theoretical pI


MKK7 Protein Structure

Crystal structure of JNK1 bound to a MKK7 docking motif
2014-08-20   Released:  2015-03-25
Deposition Author(s)
Kragelj, J., Palencia, A., Nanao, M.H., Maurin, D., Bouvignies, G., Blackledge, M., Ringkjobing-Jensen, M.
Homo sapiens
Expression System
Escherichia coli BL21(DE3)
Experimental Data Snapshot
2.3400 Å
R-Value Free
R-Value Work
4UX9 From PDB

Human MKK7 protein Secondary structure

MKK7 Protein Interaction

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