MAPK11 Protein Overview: Sequence, Structure, Function and Protein Interaction

MAPK11 Protein Overview

Mitogen-activated protein kinase (MAPK) cascades represent one of the major signal systems used by eukaryotic cells to transduce extracellular signals into cellular responses. Four MAPK subgroups have been identified in humans: the extracellular signal-regulated kinases (ERKs), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPKs), the ERK5/BMK protein (602521), and the p38 MAP kinases. MAPKs are activated by dual-specificity MAPK kinases (MAPKKs; see 602425).

MAPK11 protein family

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

MAPK11 protein name

Recommended name
Mitogen-activated protein kinase 11
Short name
MAP kinase 11||MAPK 11||MAP kinase p38 beta||
Aliases
p38-2, p38Beta, SAPK2
Alternative name
Mitogen-activated protein kinase p38 beta Stress-activated protein kinase 2b p38-2

MAPK11 Protein Sequence

Species Human MAPK11 protein
Length 364
Mass (Da) 41357
Sequence Human MAPK11 protein sequence
Species Mouse MAPK11 protein
Length 364
Mass (Da) 41397
Sequence Mouse MAPK11 protein sequence
Species
Length
Mass (Da)
Sequence

MAPK11 Protein Molecular Weight & PI

Mitogen-activated protein kinase 11 (EC 2.7.11.24) (MAP kinase 11) (MAPK 11) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-364 Mitogen-activated protein kinase 11.

Molecular weight (Da)

41357.26

Theoretical pI

5.56

MAPK11 Protein Structure

The structure of p38beta C119S, C162S in complex with a dihydroquinazolinone inhibitor
Deposited
2009-02-21   Released:  2009-07-21
Deposition Author(s)
Scapin, G., Patel, S.B.
Organism(s)
Homo sapiens
Expression System
Escherichia coli
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.0500 Å
R-Value Free
0.275
R-Value Work
0.222
3GC9 From PDB

Human MAPK11 protein Secondary structure

MAPK11 Protein Interaction

Bulk Order of Recombinant MAPK11 Protein

Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the website, our customer specialist will get back to you in 24 hours by email.

Custom Recombinant Protein Production Service Features

  • Over 10 years' experience for 6000+ recombinant proteins production.
  • One-stop service from gene synthesis and vector construction to protein expression and purification.
  • Multiple protein expression systems: bacterial, yeast, baculovirus-insect and mammalian expression system.
  • Multiple purification systems (30+) to choose.
  • High R & D ability with over 1000 new proteins per year and quick problem-solving ability.
  • Close to 100 bioreactors with various volume between 2-1000 L to guarantee high-throughput and large-scale production.

Custom Recombinant Protein Production Service Advantages

  • High-efficiency expression vectors
  • High cell density culturing
  • Proprietary medium formulation
  • >6000 proteins expression and purification experience
  • High-efficiency expression vectors
  • High cell density culturing

Recombinant Protein Production Service Description

We offer one-stop services for recombinant protein production using our advanced protein expression platform technologies. Our full services include protein gene synthesis, protein codon optimization, protein expression vector design, large scale cell culture and fermentation, protein purification, and protein quality control testing. We offer significant cost saving advantages and record speed in protein expression and bulk production. We also have extensive experiences and expertise in handling various types of recombinant protein purification projects, with or without purification tags.