Interferon alpha 10/IFNA10 Protein Overview: Sequence, Structure, Function and Protein Interaction

Interferon alpha 10/IFNA10 Protein Overview

Interferon alpha 10/IFNA10 protein family

Belongs to the alpha/beta interferon family.

Interferon alpha 10/IFNA10 protein name

Recommended name
Interferon alpha-10
Short name
IFN-alpha-10||LeIF C
Aliases
IFN-alphaC
Alternative name
Interferon alpha-6L Interferon alpha-C

Interferon alpha 10/IFNA10 Protein Sequence

Species Human Interferon alpha 10/IFNA10 protein
Length 189
Mass (Da) 21835
Sequence Human Interferon alpha 10/IFNA10 protein sequence
Species
Length
Mass (Da)
Sequence
Species
Length
Mass (Da)
Sequence

Interferon alpha 10/IFNA10 Protein Molecular Weight & PI

Interferon alpha-10 precursor (IFN-alpha-10) (Interferon alpha-6L) (Interferon alpha-C) (LeIF C) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 24-189 Interferon alpha-10.

Molecular weight (Da)

19406.13

Theoretical pI

5.68

Interferon alpha 10/IFNA10 Protein Interaction

Recombinant Interferon alpha 10/IFNA10 Protein Feature

Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc Tag)

High Purity
> 85 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
High Activity
Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 20-80 pg/mL.

Recombinant Interferon alpha 10/IFNA10 protein citations

Title
Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn's disease patients
Year
2015
Author
Xiao, CX;Xiao, JJ;Xu, HZ;Wang, HH;Chen, X;Liu, YS;Li, P;Shi, Y;Nie, YZ;Li, S;Wu, KC;Liu, ZJ;Ren, JL;Guleng, B;
Journal
Sci Rep

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