Integrin alpha 2 Gene Sequence, Family, Fuction and Expression Information
Integrin alpha 2 cDNA / Gene Overview
ITGA2 gene / cDNA is a protein-coding gene which located on 5q11.2. The ITGA2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.233 organisms have orthologs with human gene ITGA2.
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Integrin alpha 2 cDNA / Gene Sequence
LOCUS NM_002203 7878 bp mRNA linear PRI 08-JUL-2018
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