IL36RN/IL-1F5 Gene Sequence, Family, Fuction and Expression Information

IL36RN/IL-1F5 cDNA / Gene Overview

IL36RN gene / cDNA is a protein-coding gene which located on 2q14.1. The IL36RN gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.99 organisms have orthologs with human gene IL36RN.

IL36RN/IL-1F5 cDNA / Gene Function

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

IL36RN/IL-1F5 cDNA / Gene Sequence

LOCUS
LOCUS NM_173170 2689 bp mRNA linear PRI 23-JUN-2018
DEFINITION
Homo sapiens interleukin 36 receptor antagonist (IL36RN), transcript variant 2, mRNA.
ACCESSION
NM_173170
VERSION
NM_173170.1

This sequence information is just for reference only.

IL36RN/IL-1F5 Family & Reagents

Gene family

IL36RN/IL-1F5 Gene family reagents (Interleukins)

Approved Symbol Reagent list
IL11
IL22
IL13
IL37
IL6
IL18
IL7
IL20
IL23A
IL21
Approved Symbol Reagent list
IL25
IL12B
IL12A
CXCL8
IL15
IL31
IL4
IL17F
IL1RN
IL9

IL36RN/IL-1F5 cDNA / Gene Alias

  • family of interleukin 1-delta
  • FIL1
  • FIL1(DELTA)
  • FIL1D
  • IL-1 related protein 3
  • IL-1F5
  • IL1HY1
  • IL1L1
  • IL1RP3
  • IL36RA
  • interleukin-1 HY1
  • interleukin-1 receptor antagonist homolog 1
  • MGC29840

IL36RN/IL-1F5 cDNA / Gene Expression

Biased expression in skin (RPKM 14.6), esophagus (RPKM 6.5) and 1 other tissue