IL36RN/IL-1F5 Gene Sequence, Family, Fuction and Expression Information
IL36RN/IL-1F5 cDNA / Gene Overview
IL36RN gene / cDNA is a protein-coding gene which located on 2q14.1. The IL36RN gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.99 organisms have orthologs with human gene IL36RN.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
IL36RN/IL-1F5 cDNA / Gene Sequence
LOCUS NM_173170 2689 bp mRNA linear PRI 23-JUN-2018
Biased expression in skin (RPKM 14.6), esophagus (RPKM 6.5) and 1 other tissue
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