IL1F10 Protein Overview: Sequence, Structure, Function and Protein Interaction

IL1F10 Protein Overview

IL1F10, or IL38, binds to IL36R (IL1RL2; 604512) and inhibits production of various other cytokines (van de Veerdonk et al., 2012).

IL1F10 protein family

Belongs to the IL-1 family.

IL1F10 protein name

Recommended name
Interleukin-1 family member 10
Short name
IL-1F10||FIL1 theta||IL-1HY2||IL-1 theta||IL-
Aliases
FIL1- theta, FKSG75, IL-1F10, IL-1HY2, IL1-theta, interleukin-1 receptor antagonist FKSG75, MGC11983, MGC119832, MGC119833
Alternative name
Family of interleukin 1-theta Interleukin-1 HY2 Interleukin-1 theta Interleukin-38

IL1F10 Protein Sequence

Species Human IL1F10 protein
Length 152
Mass (Da) 16943
Sequence Human IL1F10 protein sequence
Species Mouse IL1F10 protein
Length 152
Mass (Da) 17078
Sequence Mouse IL1F10 protein sequence
Species
Length
Mass (Da)
Sequence

IL1F10 Protein Molecular Weight & PI

Interleukin-1 family member 10 (IL-1F10) (Family of interleukin 1-theta) (FIL1 theta) (Interleukin-1 HY2) (IL-1HY2) (Interleukin-1 theta) (IL-1 theta) (Interleukin-38) (IL-38) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-152 Interleukin-1 family member 10.

Molecular weight (Da)

16943.3

Theoretical pI

4.94

IL1F10 Protein Structure

CRYSTAL STRUCTURE OF IL-38
Deposited
2015-05-27   Released:  2016-06-01
Deposition Author(s)
Guenther, S., Sundberg, E.J.
Organism(s)
Homo sapiens
Expression System
Escherichia coli BL21(DE3)
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
1.3100 Å
R-Value Free
0.160
R-Value Work
0.138
5BOW From PDB

Human IL1F10 protein Secondary structure

IL1F10 Protein Interaction

Recombinant IL1F10 Protein Feature

IL1F10 Protein, Human, Recombinant (His Tag)

High Purity
> 90 % as determined by SDS-PAGE.
Low Endotoxin
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