FHL1 Gene Sequence, Family, Fuction and Expression Information

FHL1 cDNA / Gene Overview

FHL1 cDNA / gene is a gene with protein product which located on Xq26.3. The FHL1 gene is conserved in Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 232 organisms have orthologs with human gene FHL1.

FHL1 cDNA / Gene Function

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009]

FHL1 cDNA / Gene Sequence

LOCUS
HSU60115 2254 bp mRNA linear PRI 15-MAR-1999
DEFINITION
Homo sapiens skeletal muscle LIM-protein FHL1 mRNA, complete cds.
ACCESSION
U60115
VERSION
U60115.1

This sequence information is just for reference only.

FHL1 Family & Reagents

Gene family

FHL1 Gene family reagents (LIM domain containing)

Approved Symbol Reagent list
CRIP2
Approved Symbol Reagent list
CSRP1

FHL1 cDNA / Gene Alias

  • bA535K18.1
  • FHL1B
  • FLH1A
  • Four-and-a-half LIM domains 1
  • KYO-T
  • LIM protein SLIMMER
  • MGC111107
  • SLIM1
  • XMPMA

FHL1 cDNA / Gene Expression

Broad expression in heart (RPKM 286.6), fat (RPKM 281.6) and 18 other tissues