eNOS Gene Sequence, Family, Fuction and Expression Information
eNOS cDNA / Gene Overview
Nos3 gene / cDNA is a protein-coding gene which located on 7q36.1. The NOS3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and frog.140 organisms have orthologs with human gene NOS3.
eNOS cDNA / Gene Function
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
eNOS cDNA / Gene Sequence
LOCUS NM_000603 4345 bp mRNA linear PRI 05-AUG-2018
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