eNOS Gene Sequence, Family, Fuction and Expression Information

eNOS cDNA / Gene Overview

Nos3 gene / cDNA is a protein-coding gene which located on 7q36.1. The NOS3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and frog.140 organisms have orthologs with human gene NOS3.

eNOS cDNA / Gene Function

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]

eNOS cDNA / Gene Sequence

LOCUS
LOCUS NM_000603 4345 bp mRNA linear PRI 05-AUG-2018
DEFINITION
Homo sapiens nitric oxide synthase 3 (NOS3), transcript variant 1, mRNA.
ACCESSION
NM_000603
VERSION
NM_000603.4

This sequence information is just for reference only.

eNOS cDNA / Gene Alias

  • ECNOS
  • endothelial nitric oxide synthase
  • eNOS

eNOS cDNA / Gene Expression

Biased expression in spleen (RPKM 28.4), placenta (RPKM 4.0) and 11 other tissues