BID Gene Sequence, Family, Fuction and Expression Information
BID cDNA / Gene Overview
BID gene / cDNA is a protein-coding gene which located on 22q11.21. The BID gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.189 organisms have orthologs with human gene BID.
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
BID cDNA / Gene Sequence
LOCUS NM_197966 2535 bp mRNA linear PRI 03-JUN-2018
Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA.
This sequence information is just for reference only.
BID Gene family reagents (BCL2 homology region 3 (BH3) only)
BID cDNA / Gene Expression
Ubiquitous expression in bone marrow (RPKM 13.8), brain (RPKM 9.4) and 24 other tissues
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