Actin Protein Overview: Sequence, Structure, Function and Protein Interaction

Actin Protein Overview

Actin reagents

The ACTA1 gene encodes skeletal muscle alpha-actin, the principal actin isoform in adult skeletal muscle, which forms the core of the thin filament of the sarcomere where it interacts with a variety of proteins to produce the force for muscle contraction (Laing et al., 2009).

Actin protein family

Belongs to the actin family.

Actin protein name

Recommended name
Actin, alpha skeletal muscle
Aliases
NEM3, nemaline myopathy type 3
Alternative name
Alpha-actin-1 Actin, alpha skeletal muscle, intermediate form

Actin Protein Sequence

Species Human Actin protein
Length 377
Mass (Da) 42051
Sequence Human Actin protein sequence
Species Mouse Actin protein
Length 377
Mass (Da) 42051
Sequence Mouse Actin protein sequence
Species Rat Actin protein
Length 377
Mass (Da) 42051
Sequence Rat Actin protein sequence

Actin Protein Molecular Weight & PI

Actin, alpha skeletal muscle precursor (Alpha-actin-1) [Contains: Actin, alpha skeletal muscle, intermediate form]Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 2-377 Actin, alpha skeletal muscle,

Molecular weight (Da)

41919.84

Theoretical pI

5.23

Actin Protein Interaction

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