ACOX1 Protein Overview: Sequence, Structure, Function and Protein Interaction

ACOX1 Protein Overview

ACOX1 reagents

Peroxisomal beta-oxidation of fatty acids is catalyzed by enzymes that are immunologically distinct from the analogous mitochondrial enzymes. The ACOX1 gene encodes peroxisomal acyl-CoA oxidase (EC, the first and rate-limiting enzyme in the peroxisomal fatty acid beta-oxidation pathway. Hydrogen peroxide is a byproduct of acyl-CoA oxidase activity (Fournier et al., 1994; Li et al., 2000). See also ACOX2 (601641), which encodes the branched-chain peroxisomal acyl-CoA oxidase, and ACOX3 (603402), which encodes the pristanoyl peroxisomal acyl-CoA oxidase.

ACOX1 protein family

Belongs to the acyl-CoA oxidase family.

ACOX1 protein name

Recommended name
Peroxisomal acyl-coenzyme A oxidase 1
Short name
PALMCOX, palmitoyl-CoA oxidase
Alternative name
Palmitoyl-CoA oxidase1 Straight-chain acyl-CoA oxidase SCOX

ACOX1 Protein Sequence

Species Human ACOX1 protein
Length 660
Mass (Da) 74424
Sequence Human ACOX1 protein sequence
Species Mouse ACOX1 protein
Length 661
Mass (Da) 74649
Sequence Mouse ACOX1 protein sequence
Species Rat ACOX1 protein
Length 661
Mass (Da) 74679
Sequence Rat ACOX1 protein sequence

ACOX1 Protein Molecular Weight & PI

Peroxisomal acyl-coenzyme A oxidase 1 (EC (AOX) (Palmitoyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) (SCOX)Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-660 Peroxisomal acyl-coenzyme A oxidase 1.

Molecular weight (Da)


Theoretical pI


ACOX1 Protein Interaction

Recombinant ACOX1 Protein Feature

ACOX1 Protein, Human, Recombinant (His Tag)

High Purity
> 85 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method

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