ACOT13/THEM2 Protein Overview: Sequence, Structure, Function and Protein Interaction

ACOT13/THEM2 Protein Overview

ACOT13/THEM2 reagents

Thioesterases, such as ACOT13, function in biodegradation pathways and deacylation of palmitoylated or myristoylated proteins, in fatty acid and polyketide synthesis, and in regulation of lipid composition and metabolism (summary by Cheng et al., 2006).

ACOT13/THEM2 protein family

Belongs to the thioesterase PaaI family.

ACOT13/THEM2 protein name

Recommended name
Acyl-coenzyme A thioesterase 13
Short name
Acyl-CoA thioesterase 13
Alternative name
Thioesterase superfamily member 2 Acyl-coenzyme A thioesterase 13, N-terminally processed

ACOT13/THEM2 Gene family protein

ACOT13/THEM2 Protein Sequence

Species Human ACOT13/THEM2 protein
Length 140
Mass (Da) 14960
Sequence Human ACOT13/THEM2 protein sequence
Species Mouse ACOT13/THEM2 protein
Length 140
Mass (Da) 15183
Sequence Mouse ACOT13/THEM2 protein sequence
Mass (Da)

ACOT13/THEM2 Protein Molecular Weight & PI

Acyl-coenzyme A thioesterase 13 (EC 3.1.2.-) (Acyl-CoA thioesterase 13) (Thioesterase superfamily member 2) [Contains: Acyl-coenzyme A thioesterase 13, N-terminally processed]Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-140 Acyl-coenzyme A thioesterase 13.

Molecular weight (Da)


Theoretical pI


ACOT13/THEM2 Protein Structure

Crystal structure and function of human thioesterase superfamily member 2(THEM2)
2005-11-14   Released:  2006-10-10
Deposition Author(s)
Cheng, Z., Song, F., Shan, X., Wang, Y., Wei, Z., Gong, W.
Homo sapiens
Expression System
Escherichia coli BL21(DE3)
Experimental Data Snapshot
2.3000 Å
R-Value Free
R-Value Work
2F0X From PDB

Human ACOT13/THEM2 protein Secondary structure

ACOT13/THEM2 Protein Interaction

Recombinant ACOT13/THEM2 Protein Feature

ACOT13/THEM2 Protein, Human, Recombinant (His Tag)

High Purity
> 85 % as determined by SDS-PAGE
Low Endotoxin
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