Acid Phosphatase/ACP1 Protein Overview: Sequence, Structure, Function and Protein Interaction

Acid Phosphatase/ACP1 Protein Overview

Acid Phosphatase/ACP1 reagents

Wo et al. (1992) cloned genes encoding 2 low molecular weight phosphotyrosyl protein phosphatases from a human placenta cDNA library. They were found to have identical nucleotide sequences, with the exception of a 108-bp segment in the middle of the open reading frame. From further studies they concluded that the 2 represent the fast and slow electrophoretic forms of red cell acid phosphatase and that this enzyme is not unique to the red cell but instead is expressed in all human tissues.

Acid Phosphatase/ACP1 protein family

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Acid Phosphatase/ACP1 protein name

Recommended name
Low molecular weight phosphotyrosine protein phosphatase
Short name
LMW-PTP||LMW-PTPase
Aliases
acid phosphatase of erythrocyte, HAAP, LMWPTP, LMW-PTP, low molecular weight phosphotyrosine protein phosphatase, red cell acid phosphatase
Alternative name
Adipocyte acid phosphatase Low molecular weight cytosolic acid phosphatase Red cell acid phosphatase 1

Acid Phosphatase/ACP1 Gene family protein

Acid Phosphatase/ACP1 Protein Sequence

Species Human Acid Phosphatase/ACP1 protein
Length 158
Mass (Da) 18042
Sequence Human Acid Phosphatase/ACP1 protein sequence
Species Mouse Acid Phosphatase/ACP1 protein
Length 158
Mass (Da) 18192
Sequence Mouse Acid Phosphatase/ACP1 protein sequence
Species Rat Acid Phosphatase/ACP1 protein
Length 158
Mass (Da) 18152
Sequence Rat Acid Phosphatase/ACP1 protein sequence

Acid Phosphatase/ACP1 Protein Molecular Weight & PI

Low molecular weight phosphotyrosine protein phosphatase (EC 3.1.3.48) (LMW-PTP) (LMW-PTPase) (Adipocyte acid phosphatase) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1)Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 2-158 Low molecular weight phosphotyrosine

Molecular weight (Da)

17911.29

Theoretical pI

6.35

Acid Phosphatase/ACP1 Protein Structure

Crystal Structure of Human B-form Low Molecular Weight Phosphotyrosyl Phosphatase at 1.6 Angstrom Resolution
Deposited
2004-11-02   Released:  2005-11-01
Deposition Author(s)
Stauffacher, C.V., Zabell, A.P.R.
Organism(s)
Homo sapiens
Expression System
Escherichia coli BL21(DE3)
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
1.6300 Å
R-Value Free
0.216
R-Value Work
0.158
1XWW From PDB

Human Acid Phosphatase/ACP1 protein Secondary structure

Acid Phosphatase/ACP1 Protein Interaction

Recombinant Acid Phosphatase/ACP1 Protein Feature

Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST Tag)

High Purity
> 88 % as determined by SDS-PAGE
Low Endotoxin
Please contact us for more information.
High Activity
Measured by its ability to cleave a substrate, pNitrophenyl phosphate (pNPP). The specific activity is >65,000 pmol/min/μg.

Bulk Order of Recombinant Acid Phosphatase/ACP1 Protein

Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the website, our customer specialist will get back to you in 24 hours by email.

Custom Recombinant Acid Phosphatase/ACP1 Protein Service

Custom Recombinant Protein Production Service Features

  • Over 10 years' experience for 6000+ recombinant proteins production.
  • One-stop service from gene synthesis and vector construction to protein expression and purification.
  • Multiple protein expression systems: bacterial, yeast, baculovirus-insect and mammalian expression system.
  • Multiple purification systems (30+) to choose.
  • High R & D ability with over 1000 new proteins per year and quick problem-solving ability.
  • Close to 100 bioreactors with various volume between 2-1000 L to guarantee high-throughput and large-scale production.

Custom Recombinant Protein Production Service Advantages

  • High-efficiency expression vectors
  • High cell density culturing
  • Proprietary medium formulation
  • >6000 proteins expression and purification experience
  • High-efficiency expression vectors
  • High cell density culturing

Recombinant Protein Production Service Description

We offer one-stop services for recombinant protein production using our advanced protein expression platform technologies. Our full services include protein gene synthesis, protein codon optimization, protein expression vector design, large scale cell culture and fermentation, protein purification, and protein quality control testing. We offer significant cost saving advantages and record speed in protein expression and bulk production. We also have extensive experiences and expertise in handling various types of recombinant protein purification projects, with or without purification tags.