ACADS Protein Overview: Sequence, Structure, Function and Protein Interaction

ACADS Protein Overview

ACADS reagents

Naito et al. (1988, 1989) cloned and sequenced cDNAs encoding the precursor of human placental SCAD (EC The encoded precursor is 412 amino acids long. The sequence includes a 24-amino acid leader peptide moiety. Like the other 4 enzymes belonging to the acyl-CoA dehydrogenase family of genes, SCAD is a tetrameric mitochondrial flavoprotein. It is synthesized as a 44-kD precursor, transported into mitochondria, and proteolytically processed to its 41-kD mature form. Comparison of SCAD and MCAD (607008) showed a high degree of homology, suggesting that these enzymes evolved from a common ancestral gene and belong to a gene family.

ACADS protein family

Belongs to the acyl-CoA dehydrogenase family.

ACADS protein name

Recommended name
Short-chain specific acyl-CoA dehydrogenase, mitochondrial

ACADS Gene family protein

Acyl-CoA dehydrogenase family
Approved symbol Common name
GCDH GCDH protein, recombinant
IVD IVD protein, recombinant

ACADS Protein Molecular Weight & PI

The parameters have been computed for the following feature

FT CHAIN 25-412 Short-chain specific acyl-CoA

Molecular weight (Da)


Theoretical pI


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