ABCC11 Information: ABCC11 Protein, ABCC11 Antibody and ABCC11 Gene

ABCC11 Gene family

ABCC11 Protein

ABCC11 protein function

Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides (PubMed:12764137, PubMed:15537867). Enhances the cellular extrusion of cAMP and cGMP (PubMed:12764137, PubMed:15537867). Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate (PubMed:15537867, PubMed:25896536). Probably functions to secrete earwax (PubMed:16444273, PubMed:19383836). Required for the secretion of components contributing to axillary odor formation (PubMed:19710689).

ABCC11 protein expression

Tissue specificity

Expressed in ceruminous apocrine gland (at protein level) (PubMed:19383836, PubMed:19710689). Expressed in many tissues. Not expressed in kidney, spleen and colon. Highly expressed in breast cancer. Expressed at moderate levels in normal breast and testis and at very low levels in liver, brain and placenta.

ABCC11 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    1,382.00
  • Mass (Da)
    154.00

ABCC11 Antibody

There are 1 ABCC11 antibodies which are validated in multiple tissues with various applications, including IHC-P. There are 1 ABCC11 antibody for IHC-P. Among all these ABCC11 antibodies, there are 1 anti-ABCC11 rabbit polyclonal antibodies . All the ABCC11 anbodies are produced in house and all are in stock. ABCC11 antibody customerized service is available.

ABCC11 Gene

ABCC11 cDNA / gene is a gene with protein product which located on 16q12.1. The ABCC11 gene is conserved in chimpanzee, Rhesus monkey, and dog. 84 organisms have orthologs with human gene ABCC11.