ABCB6 Protein Overview: Sequence, Structure, Function and Protein Interaction

ABCB6 Protein Overview

ABCB6 reagents

For background information on the ATP-binding cassette (ABC) family of transporter proteins, see ABCA4 (601691). In addition to the 'full' ABC transporters with 2 transmembrane domains and 2 nucleotide-binding domains, there are 'half' proteins that contain only 1 of each domain (e.g., ABCB1, 171050). Full transporters are usually found in the plasma membrane, whereas half transporters are found in subcellular organelles. ABCB6 is located in the outer mitochondrial membrane and is required for mitochondrial porphyrin uptake (Krishnamurthy et al., 2006).

ABCB6 protein family

Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.

ABCB6 protein name

Recommended name
ATP-binding cassette sub-family B member 6, mitochondrial
Aliases
ATP-binding cassette half-transporter, EST45597, MTABC3, umat

ABCB6 Protein Molecular Weight & PI

The parameters have been computed for the following feature

FT CHAIN 1-842 ATP-binding cassette sub-family B member

Molecular weight (Da)

93885.56

Theoretical pI

8.75

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