B Cell Receptor

B cell, also called B lymphocyte, developed in bone marrow of most mammals, that circulates in the blood and lymph. One of the main functions of a B cell is antibody production, which aids in adaptive immunity, complement activation, and induction of allergic responses.

When encountering a particular foreign antigen, B cell can possesss a functioning B cell receptor and high affinity antibodies and differentiate into a clone of plasma cells that secrete a specific antibody and a clone of memory B cells that make the antibody on subsequent encounters.

1. Seda, V. et al. (2015). B‐cell receptor signalling and its crosstalk with other pathways in normal and malignant cells. European journal of haematology, 94(3), 193-205.