Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyze, chemical reactions. The other enzymes, as Carbonic Anhydrases (CA), which a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. The tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA. Almost all metabolic processes in the cell need enzymes in order to occur at rates fast enough to sustain.
The ubiquitin proteasome system (UPS) is the main system for controlled protein degradation and a key regulator of fundamental cellular processes. Dysfunctions of this system can disrupt cellular homeostasis and lead to a host of disorders. In normally functioning cells, the covalent linkage of ubiquitin or ubiquitin-like protein to a target protein changes the target protein's surface.
The oxidative stress produced by these chemicals can damage cells and tissues, for example an overdose of the analgesic paracetamol (acetaminophen) can fatally damage the liver, partly through its production of reactive oxygen species.
Sino Biological offers a comprehensive set of tools for Enzymes related studies, including recombinant proteins, antibodies (rabbit mAbs, mouse mAbs, rabbit pAbs), ELISA kits, and ORF cDNA clones.
Non-receptor tyrosine kinases regulate multiple cellular processes, such as proliferation, differentiation and adhesion, and are also critical to regulating immune systems. Furthermore, studies suggest that non-receptor tyrosine kinases are targets for cancer therapies. For example, Src, a non-receptor tyrosine kinase, is the first proto-oncogene, which is resulted in two Nobel Prize to date.