PSG1 Protein, Human, Recombinant (His Tag)

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PSG1 Protein, Human, Recombinant (His Tag): Product Information

Purity
> 95 % as determined by SDS-PAGE.
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the human PSG1 (NP_001171754.1) (Met1-Pro419) was expressed with a polyhistidine tag at the C-terminus.
Accession#
Expressed Host
HEK293 Cells
Species
Human
Predicted N Terminal
Gln 35
Molecule Mass
The recombinant human PSG1 consists 396 amino acids and predicts a molecular mass of 44.9 kDa.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

PSG1 Protein, Human, Recombinant (His Tag): Images

PSG1 Protein, Human, Recombinant (His Tag): Synonyms

B1G1 Protein, Human; CD66f Protein, Human; DHFRP2 Protein, Human; FL-NCA-1/2 Protein, Human; PBG1 Protein, Human; PS-beta-C/D Protein, Human; PS-beta-G-1 Protein, Human; PSBG-1 Protein, Human; PSBG1 Protein, Human; PSG95 Protein, Human; PSGGA Protein, Human; PSGIIA Protein, Human; SP1 Protein, Human

PSG1 Background Information

Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human and murine PSG family have been shown to induce anti-inflammatory cytokines from monocytes and macrophages and to stimulate angiogenesis.Two distinct domains of PSG1 are involved in the regulation of TGF-beta1 and provide a mechanistic framework for how PSGs modulate the immunoregulatory environment at the maternal-fetal interface for successful pregnancy outcome.
Full Name
pregnancy specific beta-1-glycoprotein 1
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