Human IL-37 qPCR Primer Pair

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Human IL-37 qPCR Primer Pair: General Information

Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.
***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages

Unique Primer Design

To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.

Strict Validation Process

Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.

Uniform PCR conditions, Saving time and cost

~100% amplification curve, ensuring the accuracy of the RNA quantitative

Human IL-37 qPCR Primer Pair: Synonyms

FIL1 qPCR Primer Pairs, Human; FIL1(ZETA) qPCR Primer Pairs, Human; FIL1Z qPCR Primer Pairs, Human; IL-1F7 qPCR Primer Pairs, Human; IL-1H qPCR Primer Pairs, Human; IL-1H4 qPCR Primer Pairs, Human; IL-1RP1 qPCR Primer Pairs, Human; IL-37 qPCR Primer Pairs, Human; IL1F7 qPCR Primer Pairs, Human; IL1H4 qPCR Primer Pairs, Human; IL1RP1 qPCR Primer Pairs, Human; IL37 qPCR Primer Pairs, Human

IL-37 Background Information

Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases, and/or cancer. Through constructing an adenoviral vector that allows high-level expression in murine and human cells, it has been demonstrated that the ability of adenovirus-mediated gene transfer of IL1F7 to induce an IL-12- and Fas ligand-dependent anti-tumor response. Complete inhibition of tumor growth was observed following multiple injections of IL1F7 in most animals. These results suggest that IL1F7 could play a role in both innate and adaptive immune responses, similar to IL-18. Moreover, IL1F7 could be useful for cancer gene therapy.
Full Name
interleukin 37
Related Pathways
  • IL1 signaling pathway
    IL1 signaling pathway
References
  • Gao W, et al. (2003) Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity. J Immunol. 170 (1): 107-13.
  • Bufler P, et al. (2002) A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc Natl Acad Sci. 99 (21): 13723-8.
  • Kumar S, et al. (2002) Interleukin-1F7B (IL-1H4 / IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production. Cytokine. 18 (2): 61-71.

IL-37 qPCR Primer Pairs, Human, Related Products

  • Interleukin-18, Functional IL-18 Receptor and IL-18 Binding Protein Expression in Active and Latent Tuberculosis
    Author
    Wawrocki, S;Kielnierowski, G;Rudnicka, W;Seweryn, M;Druszczynska, M;
    Year
    2020
    Journal
    Pathogens
    Application
    qPCR
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