Anti-Doppel / PRND Antibody

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Anti-Doppel / PRND Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Doppel / PRND Antibody
Validated applications
WB,ELISA
Species reactivity
Reacts with: Human
Specificity
Human Doppel / PRND
Immunogen
Recombinant Human PRND protein (Catalog#15113-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human PRND (rh PRND; Catalog#15113-H08H; NP_036541.2; Met1-Gly152). PRND specific IgG was purified by Human PRND affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Doppel / PRND Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
WB 1:500-1:1000
ELISA 1:25000-1:50000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Doppel / PRND Antibody (Rabbit Polyclonal antibody) Images

Anti-PRND rabbit polyclonal antibody at 1:500 dilution

Lane A: Mouse spleen Tissue Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:20 kDa

Observed band size:18 kDa

Anti-Doppel / PRND Antibody: Alternative Names

Anti-dJ1068H6.4 Antibody; Anti-DOPPEL Antibody; Anti-DPL Antibody; Anti-PrPLP Antibody

Doppel / PRND Background Information

Doppel (PRND) is a paralogue of the mammalian prion (PRNP) gene. It is abundant in testis and, unlike PRNP, it is expressed at low levels in the adult central nervous system (CNS). Besides, doppel overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons.Prion-related protein doppel gene (PRND), as an essential member of the mammalian prion gene family, is associated with the scrapie susceptibility as well as phenotype traits, so the genetic variation of the PRND has been highly concerned recently, including the single nucleiotide polymorphism (SNP) and insertion/deletion (indel).
Full Name
prion protein 2 (dublet)

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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