IL-1 beta Matched ELISA Antibody Pair Set,Human

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IL-1 beta Matched ELISA Antibody Pair Set,Human General Information

Product name
IL-1 beta Matched ELISA Antibody Pair Set,Human
Assay type
Solid Phase Sandwich ELISA
Specificity
Quantitative determination of Human IL-1 beta
Assay range
78.13-5000 pg/mL
Materials provided
1. Capture Antibody 1 mg/mL of mouse anti-Human IL-1 beta / IL1B / IL-1F2 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 0.5 μg/mL in PBS before coating. (Catalog: # 10139-MM07)
2. Detection Antibody 0.2 mg/mL of mouse anti-Human IL-1 beta / IL1B / IL-1F2 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.5 μg/mL in Dilution Buffer before use. (Catalog: # 10139-MM09)
3. Standard Each vial contains 95 ng of recombinant Human IL-1 beta / IL1B / IL-1F2. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in Dilution Buffer, and a high standard of 5000 pg/mL is recommended.
Product overview
This IL-1 beta Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human IL-1 beta . It contains Human IL-1 beta capture antibody, Human IL-1 beta detector antibody (HRP) and a highly purified E. coli-expressed recombinant Human IL-1 beta protein. This Pair Set is at affordable price for researchers.
Shipping
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
Storage
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

IL-1 beta Matched ELISA Antibody Pair Set,Human Images

IL-1 beta Matched ELISA Antibody Pair Set,Human: Alternative Names

IL-1 Matched ELISA Antibody Pair Set, Human; IL-1 beta Matched ELISA Antibody Pair Set, Human; IL-1B Matched ELISA Antibody Pair Set, Human; IL1-BETA Matched ELISA Antibody Pair Set, Human; IL1F2 Matched ELISA Antibody Pair Set, Human

IL-1 beta Background Information

Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
Full Name
interleukin 1, beta
References
  • Kim SH, et al. (2008) Association of -31TC and -511 CT polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis. 14:2109-16.
  • Wang ZC, et al. (2002) T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun. 3(1): 38-42.
  • Mattuzzi S, et al. (2007) Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol. 34(5): 997-1004.
  • Rheumatoid arthritis-associated microRNA-155 targets SOCS1 and upregulates TNF-α and IL-1β in PBMCs
    Author
    Li, X;Tian, F;Wang, F;
    Year
    2013
    Journal
    Int J Mol Sci
  • LncRNA-MEG3 alleviates high glucose induced inflammation and apoptosis of retina epithelial cells via regulating miR-34a/SIRT1 axis
    Author
    Tong, P;Peng, QH;Gu, LM;Xie, WW;Li, WJ;
    Year
    2018
    Journal
    Exp. Mol. Pathol.
    Application
    ELISA
  • Fatty acylCoA synthetase FadD13 regulates proinflammatory cytokine secretion dependent on the NF-κB signalling pathway by binding to eEF1A1
    Author
    Wei, S;Wang, D;Li, H;Bi, L;Deng, J;Zhu, G;Zhang, J;Li, C;Li, M;Fang, Y;Zhang, G;Chen, J;Tao, S;Zhang, XE;
    Year
    2019
    Journal
    Cell. Microbiol.
    Application
    ELISA
  • AEBP1 Promotes the Occurrence and Development of Abdominal Aortic Aneurysm by Modulating Inflammation via the NF-κB Pathway
    Author
    Ren, J;Han, Y;Ren, T;Fang, H;Xu, X;Lun, Y;Jiang, H;Xin, S;Zhang, J;
    Year
    2019
    Journal
    J. Atheroscler. Thromb.
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