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EFNB2A / Ephrin B2a Antibody, Rabbit PAb

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Expression host: Human Cells  
  • Slide 1
63002-Z02H-200
63002-Z02H-100
200 µg 
100 µg 
Add to Cart
Expression host: Human Cells  
  • Slide 1
63002-Z08H-200
63002-Z08H-100
200 µg 
100 µg 
Add to Cart

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EFNB2A / Ephrin B2a antibody Background

Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.

Danio rerio (zebrafish) EFNB2A / Ephrin B2a antibody References
  • Shaw KM. et al., 2006, Dev Dyn. 235 (7): 1753-60.
  • Kemp HA. et al., 2009, Dev Biol. 327 (2): 313-26.
  • Patten SA. et al., 2012, PLoS One. 7 (2): e31650.
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