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Human SARS Coronavirus Spike S1 Subunit Protein Antibody, Rabbit PAb

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Description: Active  
Expression host: Human Cells  
  • Slide 1
40021-V08H-50
40021-V08H-5
40021-V08H-20
40021-V08H-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Expression host: Baculovirus-Insect cells  
  • Slide 1
40150-V08B1-50
40150-V08B1-5
40150-V08B1-20
40150-V08B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Expression host: Baculovirus-Insect cells  
  • Slide 1
40150-V31B2-50
40150-V31B2-5
40150-V31B2-20
40150-V31B2-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Expression host: Baculovirus-Insect cells  
  • Slide 1
40150-V08B2-50
40150-V08B2-5
40150-V08B2-20
40150-V08B2-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description:   
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40070-V08B-50
40070-V08B-5
40070-V08B-20
40070-V08B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
40069-V08H-50
40069-V08H-5
40069-V08H-20
40069-V08H-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40069-V08B-50
40069-V08B-5
40069-V08B-20
40069-V08B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40071-V31B-50
40071-V31B-5
40071-V31B-20
40071-V31B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description:   
Expression host: Baculovirus-Insect cells  
  • Slide 1
40071-V31B1-50
40071-V31B1-5
40071-V31B1-20
40071-V31B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40069-V08B1-50
40069-V08B1-5
40069-V08B1-20
40069-V08B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description: Active  
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40071-V05B-50
40071-V05B-5
40071-V05B-20
40071-V05B-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart
Description:   
Expression host: Baculovirus-Insect Cells  
  • Slide 1
40071-V08B1-50
40071-V08B1-5
40071-V08B1-20
40071-V08B1-100
50 µg 
5 µg 
20 µg 
100 µg 
Add to Cart

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CoV Spike glycoprotein antibody Background

The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. 

SARS CoV Spike glycoprotein antibody References
  • Shen S, et al. (2007) Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS CoV. Methods Mol Biol. 379: 127-35.
  • Du L, et al. (2009) The spike protein of SARS-CoV--a target for vaccine and therapeutic development. Nat Rev Microbiol. 7 (3): 226-36.
  • Xiao X, et al. (2004) The SARS-CoV S glycoprotein. Cell Mol Life Sci. 61 (19-20): 2428-30.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"