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Human CCL17/TARC Gene ORF cDNA clone expression plasmid, C-Flag tag

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Expression host: Baculovirus-Insect Cells  
  • Slide 1
10233-H08B-50
10233-H08B-20
50 µg 
20 µg 
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Expression host: Baculovirus-Insect Cells  
  • Slide 1
10233-HNAB-50
10233-HNAB-20
50 µg 
20 µg 
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Expression host: Baculovirus-Insect Cells  
  • Slide 1
50046-MNAB-50
50046-MNAB-20
50 µg 
20 µg 
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Expression host: Baculovirus-Insect Cells  
  • Slide 1
90077-C08B-50
90077-C08B-20
50 µg 
20 µg 
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Reactivity: Human  
Application: ELISA  
    10233-RP02-50
    10233-RP02-200
    10233-RP02-100
    50 µg 
    200 µg 
    100 µg 
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    Reactivity: Human  
    Application: ELISA  
      10233-RP01-400
      10233-RP01-200
      10233-RP01-100
      400 µg 
      200 µg 
      100 µg 
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      Reactivity: Human  
      Application: ELISA  
        10233-T16-50
        10233-T16-200
        10233-T16-100
        50 µg 
        200 µg 
        100 µg 
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        Reactivity: Human  
        Application: ELISA  
          10233-MM03-50
          10233-MM03-200
          10233-MM03-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50046-RP01-400
            50046-RP01-200
            50046-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart

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            CCL17/TARC cdna-clone Background

            Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.

            Human CCL17/TARC cdna-clone References
          • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
          • Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8+ T cells. Science. 270 (5243): 1811-5.
          • Morita A, et al. (2002). Evaluation of human thymus and activation-regulated chemokine concentrations in blood using a new sandwich ELISA based on monoclonal antibodies. Clin Chim Acta. 322 (1-2): 67-75.
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