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Human EphA1/Eph Receptor A1 Gene ORF cDNA clone expression plasmid, N-His tag

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Expression host: Human Cells  
  • Slide 1
15789-H08H-20
15789-H08H-100
20 µg 
100 µg 
Add to Cart
Expression host: Human Cells  
  • Slide 1
15789-H02H-20
15789-H02H-100
20 µg 
100 µg 
Add to Cart
Expression host: Human Cells  
  • Slide 1
50827-M08H-200
50827-M08H-100
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    15789-T16-50
    15789-T16-200
    15789-T16-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Mouse  
    Application: ELISA  
      50827-RP01-400
      50827-RP01-200
      50827-RP01-100
      400 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Mouse  
      Application: ELISA  
        50827-R043-50
        50827-R043-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50827-T16-50
          50827-T16-200
          50827-T16-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart

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          EphA1/Eph Receptor A1 cdna-clone Background

          EPHA1 or EPH receptor A1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. An important role of Eph receptors and their ligands ephrins is to mediate cell-contact-dependent repulsion. Eph receptors and ephrins also act at boundaries to channel neuronal growth cones along specific pathways, restrict the migration of neural crest cells, and via bidirectional signaling prevent intermingling between hindbrain segments. Eph receptors and ephrins can also trigger an adhesive response of endothelial cells and are required for the remodeling of blood vessels. Eph receptors and ephrins have emerged as key regulators of the repulsion and adhesion of cells that underlie the establishment, maintainence, and remodeling of patterns of cellular organization. The ephrins and Eph receptors are implicated as positional labels that may guide the development of neural topographic maps.

          Human EphA1/Eph Receptor A1 cdna-clone References
        • Flanagan JG, et al. (1998) THE EPHRINS AND EPH RECEPTORS IN NEURAL DEVELOPMENT. Annual Review of Neuroscience. 21: 309-45.
        • Wilkinson DG (2000) Eph receptors and ephrins: Regulators of guidance and assembly. International Review of Cytology. 196: 177-244.
        • Zhou R. (1998) The Eph family receptors and ligands. Pharmacol. 77 (3): 151-81.
        • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"