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Mouse PCSK9/NARC1 Gene ORF cDNA clone expression plasmid, C-His tag

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Expression host: Human Cells  
  • Slide 1
10594-H08H1-50
10594-H08H1-10
50 µg 
10 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
10594-H08H-50
10594-H08H-20
10594-H08H-10
50 µg 
20 µg 
10 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
50251-M08H-20
50251-M08H-10
20 µg 
10 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
80005-R08H-20
80005-R08H-10
20 µg 
10 µg 
Add to Cart
Description: Active  
Expression host: Human Cells  
  • Slide 1
11054-K08H-20
11054-K08H-10
20 µg 
10 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    10594-MM01-50
    10594-MM01-200
    10594-MM01-100
    50 µg 
    200 µg 
    100 µg 
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    Reactivity: Human  
    Application: ELISA  
      10594-T16-50
      10594-T16-200
      10594-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10594-RM03-50
        10594-RM03-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10594-RP02-400
          10594-RP02-200
          10594-RP02-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  IHC-P  
          • Slide 1
          10594-T24-50
          10594-T24-200
          10594-T24-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  
            10594-RP01-400
            10594-RP01-200
            10594-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              50251-R106-50
              50251-R106-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: 
              • Slide 1
              • Slide 1
              • Slide 1
              50251-T26-50
              50251-T26-200
              50251-T26-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: 
                50251-R214-50
                50251-R214-100
                50251-R214-1
                50 µg 
                100 µg 
                1 mg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  
                  50251-RP01-400
                  50251-RP01-200
                  50251-RP01-100
                  400 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: ELISA  
                    50251-RP02-50
                    50251-RP02-200
                    50251-RP02-100
                    50 µg 
                    200 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Rat  
                    Application: 
                      80005-R007-50
                      80005-R007-100
                      80005-R007-1
                      50 µg 
                      100 µg 
                      1 mg 
                      Add to Cart
                      Reactivity: Rat  
                      Application: 
                        80005-MM06-50
                        80005-MM06-200
                        80005-MM06-100
                        80005-MM06-1
                        50 µg 
                        200 µg 
                        100 µg 
                        1 mg 
                        Add to Cart
                        Reactivity: Rat  
                        Application: IHC-P  
                        • Slide 1
                        80005-MM04-50
                        80005-MM04-200
                        80005-MM04-100
                        50 µg 
                        200 µg 
                        100 µg 
                        Add to Cart
                        Reactivity: Rat  
                        Application: ELISA  
                          80005-RP02-50
                          80005-RP02-200
                          80005-RP02-100
                          50 µg 
                          200 µg 
                          100 µg 
                          Add to Cart
                          Reactivity: Rat  
                          Application: ELISA  
                            80005-RP01-400
                            80005-RP01-200
                            80005-RP01-100
                            400 µg 
                            200 µg 
                            100 µg 
                            Add to Cart
                            Reactivity: Rat  
                            Application: ELISA  
                              80005-MM03-50
                              80005-MM03-200
                              80005-MM03-100
                              50 µg 
                              200 µg 
                              100 µg 
                              Add to Cart

                              PCSK9/NARC1 ELISA Pair Set

                              Detection Limit: 47 pg/ml
                              SEK80005-5
                              SEK80005-15
                              5 Plates 
                              15 Plates 
                              Add to Cart
                              Detection Limit: 62.5 pg/ml
                              SEK50251-5
                              SEK50251-15
                              5 Plates 
                              15 Plates 
                              Add to Cart

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                              PCSK9/NARC1 cdna-clone Background

                              Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

                              References

                              Mouse PCSK9/NARC1 cdna-clone References
                            • Sseidah, N.G. et al., 2003, Proc. Natl. Acad. Sci. USA. 100: 928-933.
                            • Beyer, T.P. et al., 2007, J. Lipid. Res. 48: 1488-1498
                            • Shan, L. et al., 2008, Biochem. Biophys. Res. Commun. 375: 69-73.
                            • Benjannet, S. et al., 2005, J. Biol. Chem. 279: 48865-48875.
                            • Abifadel, M. et al., 2003, Nat. Genet. 34: 154-156.
                            • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"