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Mouse CNDP2 Gene ORF cDNA clone expression plasmid, C-His tag

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Expression host: Baculovirus-Insect Cells  
  • Slide 1
10168-H08B-20
10168-H08B-10
20 µg 
10 µg 
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Description: Active  
Expression host: Baculovirus-Insect Cells  
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50246-M08B-20
50246-M08B-100
20 µg 
100 µg 
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Reactivity: Mouse  
Application: ELISA  WB  
    50246-R001-50
    50246-R001-100
    50 µg 
    100 µg 
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    Reactivity: Mouse  
    Application: ELISA  WB  IP  
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    • Slide 1
    50246-RP02-50
    50246-RP02-100
    50 µg 
    100 µg 
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    Reactivity: Mouse  
    Application: IHC-P  
    • Slide 1
    50246-R210-50
    50246-R210-100
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Mouse  
    Application: ELISA  
      50246-RP01-200
      50246-RP01-100
      200 µg 
      100 µg 
      Add to Cart

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      CNDP2 cdna-clone Background

      Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. It may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform 1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis.

      Mouse CNDP2 cdna-clone References
    • Bakker,SJ. et al., 2008, Diabetes  57 (12):e16; author reply e17. 
    • Wanic, K. et al., 2008, Diabetes  57 (9): 2547-51.
    • McDonough,CW. et al., 2009, Hum Genet 126 (2): 265-75.
    • Kaur,H. et al., 2009, J Biol Chem. 284 (21):14493-502.
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