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Human DEPE2 Gene ORF cDNA clone expression plasmid, N-HA tag

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Description:   
Expression host: Human Cells  
  • Slide 1
13806-H02H-20
13806-H02H-100
20 µg 
100 µg 
Add to Cart
Description:   
Expression host: Human Cells  
  • Slide 1
13806-H08H-50
13806-H08H-20
50 µg 
20 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    13806-RP01-400
    13806-RP01-200
    13806-RP01-100
    400 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      13806-T16-50
      13806-T16-200
      13806-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

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      DEPE2 cdna-clone Background

      DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

      Human DEPE2 cdna-clone References
    • Geetha M. Habib.et al.,2003,The FASEB Journal.8
    • Habib,G.M.,and Lieberman,M.W.1999,Adv.Exp.Med.Biol.469,295-300
    • Campbell, B. Jet al.,1984,J.Biol.Chem.259,14586-14590.
    • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"