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Mouse PFK1/PFKM Gene ORF cDNA clone expression plasmid, N-Flag tag

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Expression host: Baculovirus-Insect Cells  
  • Slide 1
14133-H20B-50
50 µg 
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PFK1/PFKM cdna-clone Background

PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Mutations in PFK1 gene have been related with glycogen storage disease type VII, also identified as Tarui disease.

Mouse PFK1/PFKM cdna-clone References
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