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Human CD155 / PVR Protein (His Tag)

DatasheetReviewsProtocols
Reactivity: Human  
Application: FCM  IF  ICC/IF  
  • Slide 1
  • Slide 1
10109-MM09-F-25
10109-MM09-F-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: FCM  
  • Slide 1
10109-MM09-A-25
10109-MM09-A-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  
  • Slide 1
10109-RP01-400
10109-RP01-200
10109-RP01-100
400 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IP  
  • Slide 1
  • Slide 1
10109-R114-50
10109-R114-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
  • Slide 1
10109-MM09-50
10109-MM09-200
10109-MM09-100
50 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  
  • Slide 1
10109-MM11-50
10109-MM11-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
  • Slide 1
10109-MM09-P-25
10109-MM09-P-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IP  
  • Slide 1
  • Slide 1
10109-RP02-50
10109-RP02-200
10109-RP02-100
50 µg 
200 µg 
100 µg 
Add to Cart
Reactivity: Mouse  
Application: FCM  
  • Slide 1
  • Slide 1
50259-R305-P-25
50259-R305-P-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Mouse  
Application: ELISA  
    50259-RP01-400
    50259-RP01-200
    50259-RP01-100
    400 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Mouse  
    Application: FCM  IF  ICC/IF  
    • Slide 1
    • Slide 1
    50259-R305-50
    50259-R305-100
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Mouse  
    Application: FCM  
    • Slide 1
    • Slide 1
    50259-R305-A-25
    50259-R305-A-100
    25 Test 
    100 Tests 
    Add to Cart
    Reactivity: Mouse  
    Application: FCM  
    • Slide 1
    • Slide 1
    50259-R305-F-25
    50259-R305-F-100
    25 Test 
    100 Tests 
    Add to Cart
    Reactivity: Mouse  
    Application: ELISA  
      50259-RP02-50
      50259-RP02-200
      50259-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Mouse  
      Application: ELISA  
        50259-R501-50
        50259-R501-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: FCM  
        • Slide 1
        50259-R305-C-25
        50259-R305-C-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50259-R001-50
          50259-R001-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Rat  
          Application: ELISA  
            80007-MM06-50
            80007-MM06-200
            80007-MM06-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  
              80007-R026-50
              80007-R026-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80007-RP02-50
                80007-RP02-200
                80007-RP02-100
                50 µg 
                200 µg 
                100 µg 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  
                  80007-RP01-400
                  80007-RP01-200
                  80007-RP01-100
                  400 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Rhesus  
                  Application: ELISA  
                    90005-RP02-50
                    90005-RP02-200
                    90005-RP02-100
                    50 µg 
                    200 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Rhesus  
                    Application: ELISA  
                      90005-RP01-400
                      90005-RP01-200
                      90005-RP01-100
                      400 µg 
                      200 µg 
                      100 µg 
                      Add to Cart
                      Reactivity: Rhesus  
                      Application: ELISA  WB  
                      • Slide 1
                      90005-MM06-50
                      90005-MM06-200
                      90005-MM06-100
                      50 µg 
                      200 µg 
                      100 µg 
                      Add to Cart

                      HP100017 

                      CD155/PVR Recombinant ProteinRelated Products

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                      CD155/PVR protein Background

                      CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.

                      Immune Checkpoint
                      Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
                      Immune Checkpoint Proteins
                      Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

                      Immunotherapy   Cancer Immunotherapy   Targeted Therapy

                      Human CD155/PVR protein References
                    • Freistadt MS, et al. (2000) Hematopoietic cells from CD155-transgenic mice express CD155 and support poliovirus replication ex vivo. Microb Pathog. 29(4): 203-12.
                    • Sato T, et al. (2004) Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions. Genes Cells. 9(9): 791-9.
                    • Kakunaga S, et al. (2004) Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. J Biol Chem. 279(35): 36419-25.
                    • Sato T, et al. (2005) Common signaling pathway is used by the trans-interaction of Necl-5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell-cell adhesion. Cancer Sci. 96(9): 578-89.
                    • Minami Y, et al. (2007) Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells. Biochem Biophys Res Commun. 352(4): 856-60.
                    • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"