NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. NCAM1 is involved in neuron-neuron adhesion, neurite fasciculation, the outgrowth of neurites, etc. It has also been shown to be involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Diseases associated with NCAM1 include Rabies and Bile Duct Cancer. Among its related pathways are Neuroscience and RET signaling.
Full Name
neural cell adhesion molecule 1
References
- Reyes AA. et al., 1991, Mol Cell Biol. 11 (3): 1654-61.
- Suzuki M. et al., 2003, J Biol Chem. 278 (49): 49459-68.
- Becker C G. et al., 1996, J Neurosci Res. 45 (2): 143-52.