MMP13 cDNA ORF Clone in Cloning Vector, Mouse

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MMP13 cDNA ORF Clone in Cloning Vector, Mouse: General Information

Gene
Species
Mouse
NCBI Ref Seq
RefSeq ORF Size
1419 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 1129C/A(P377T)
Description
Full length Clone DNA of Mouse matrix metallopeptidase 13
Plasmid
Vector
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

MMP13 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

More Information About MMP13

Entrez Gene ID

MMP13 cDNA ORF Clone in Cloning Vector, Mouse: Synonyms

Clg cDNA ORF Clone, Mouse; MMP-13 cDNA ORF Clone, Mouse; Mmp1 cDNA ORF Clone, Mouse

MMP13 Background Information

Matrix metalloproteinases (MMPs) such as MMP13 promote tumor growth and progression by mediating extracellular matrix (ECM) reorganization and regulating the biological activity of cytokines. Matrix metalloproteinase 13 (MMP13) plays a central role in the MMP activation cascade that enables degradation of the extracellular matrix and basement membranes, and it is identified as a potential driver in oral carcinogenesis.MMP13 is enriched in mature chondrocytes and is considered a prime cause of ECM degradation in the osteoarthritic articular cartilage in temporomandibular joints. A missense mutation of MMP13 causes the Missouri type of human Spondyloepimetaphyseal dysplasia (SEMD(MO)), an autosomal dominant disorder characterized by defective growth and modeling of vertebrae and long bones.
Full Name
matrix metallopeptidase 13
Research Areas
Related Pathways
  • IL17 signaling pathway
    IL17 signaling pathway
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