The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
TRH cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
TRH cDNA ORF Clone in Cloning Vector, Human: Synonyms
Pro-TRH cDNA ORF Clone, Human; TRF cDNA ORF Clone, Human
TRH Background Information
Thyrotropin-releasing hormone (TRH) is the first hypothalamic hypophysiotropic neuropeptide whose sequence has been chemically characterized. The primary structure of TRH (pGlu-His-Pro-NH(2)) has been fully conserved across the vertebrate phylum. TRH is generated from a large precursor protein that contains multiple repeats of the TRH progenitor tetrapeptide Gln-His-Pro-Gly. In all tetrapods, TRH-expressing neurons located in the hypothalamus project towards the external zone of the median eminence. TRH has an important role in the regulation of energy homeostasis, feeding behavior, thermogenesis, and autonomic regulation. TRH causes a variety of thyroidal and non-thyroidal effects, the best known being the feedback regulation of thyroid hormone levels. TRH controls energy homeostasis mainly through its Hypophysiotropic Actions to regulate circulating thyroid hormone levels.
thyrotropin releasing hormone
Singh O, et al. (2019) Thyrotropin-releasing hormone (trh) in the brain and pituitary of the teleost, clarias batrachus and its role in regulation of hypophysiotropic dopamine neurons. J Comp Neurol 527 (6): 1070-1101.
Shibusawa N, et al. (2008) Thyrotropin-releasing hormone (trh) in the cerebellum. Cerebellum 7 (1): 84-95.
Galas L, et al. (2009) Trh acts as a multifunctional hypophysiotropic factor in vertebrates. Gen Comp Endocrinol 164 (1): 40-50.
Fröhlich E, et al. (2019) The forgotten effects of thyrotropin-releasing hormone: Metabolic functions and medical applications. Front Neuroendocrinol 52 29-43.
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