ERK1/MAPK3 cDNA ORF Clone in Cloning Vector, Human
Cat: HG11545-M
Cat: HG11545-M
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ERK1/MAPK3 cDNA ORF Clone in Cloning Vector, Human: General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
1140 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for two point mutations 6G/T and 9G/T not causing the amino acid variation.
Description
Full length Clone DNA of Human mitogen-activated protein kinase 3.
Plasmid
Vector
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
ERK1/MAPK3 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
ERK1/MAPK3 cDNA ORF Clone in Cloning Vector, Human: Synonyms
ERK-1 cDNA ORF Clone, Human; ERK1 cDNA ORF Clone, Human; ERT2 cDNA ORF Clone, Human; HS44KDAP cDNA ORF Clone, Human; HUMKER1A cDNA ORF Clone, Human; p44-ERK1 cDNA ORF Clone, Human; p44-MAPK cDNA ORF Clone, Human; P44ERK1 cDNA ORF Clone, Human; P44MAPK cDNA ORF Clone, Human; PRKM3 cDNA ORF Clone, Human
ERK1/MAPK3 Background Information
The protein encoded by ERK1 gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Full Name
mitogen-activated protein kinase 3
Research Areas
Related Pathways
-
EGFR Signaling Pathway -
NF-kB (NFkB) Pathway -
TGF-beta Signaling -
TNF Signaling -
VEGF Signaling Pathway -
B Cell Receptor Signaling Pathway -
G Protein-coupled Receptors Signaling -
Jak-Stat Signaling Pathway -
MAPK-Erk Pathway -
T Cell Receptor Signaling Pathway -
Common G-Chain signaling pathway -
IL1 signaling pathway -
IL17 signaling pathway
References
- Kolb RH, Greer PM, Cao PT, Cowan KH, Yan Y. ERK1/2 Signaling Plays an Important Role in Topoisomerase II Poison-Induced G2/M Checkpoint Activation. Tan M, ed. PLoS ONE. 2012;7(11):e50281.
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