ERK1/MAPK3 cDNA ORF Clone in Cloning Vector, Human


ERK1/MAPK3 cDNA ORF Clone in Cloning Vector, Human: General Information

NCBI Ref Seq
RefSeq ORF Size
1140 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for two point mutations 6G/T and 9G/T not causing the amino acid variation.
Full length Clone DNA of Human mitogen-activated protein kinase 3.
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.

ERK1/MAPK3 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

ERK1/MAPK3 cDNA ORF Clone in Cloning Vector, Human: Synonyms

ERK-1 cDNA ORF Clone, Human; ERK1 cDNA ORF Clone, Human; ERT2 cDNA ORF Clone, Human; HS44KDAP cDNA ORF Clone, Human; HUMKER1A cDNA ORF Clone, Human; p44-ERK1 cDNA ORF Clone, Human; p44-MAPK cDNA ORF Clone, Human; P44ERK1 cDNA ORF Clone, Human; P44MAPK cDNA ORF Clone, Human; PRKM3 cDNA ORF Clone, Human

ERK1/MAPK3 Background Information

MAPK3 (Mitogen-Activated Protein Kinase 3, also known as ERK1) is a Protein Coding gene. The protein encoded by the ERK1 gene is a member of the MAP kinase family. 3 alternatively spliced human isoforms have been reported. The protein is a serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs that play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. ERK1 is widely expressed in the small intestine, colon, and other tissues. Diseases associated with MAPK3 include Neutrophil Migration and Pertussis.
Full Name
mitogen-activated protein kinase 3
Research Areas
Related Pathways
  • EGFR Signaling Pathway
    EGFR Signaling Pathway
  • NF-kB (NFkB) Pathway
    NF-kB (NFkB) Pathway
  • TGF-beta Signaling
    TGF-beta Signaling
  • TNF Signaling
    TNF Signaling
  • VEGF Signaling Pathway
    VEGF Signaling Pathway
  • B Cell Receptor Signaling Pathway
    B Cell Receptor Signaling Pathway
  • G Protein-coupled Receptors Signaling
    G Protein-coupled Receptors Signaling
  • Jak-Stat Signaling Pathway
    Jak-Stat Signaling Pathway
  • MAPK-Erk Pathway
    MAPK-Erk Pathway
  • T Cell Receptor Signaling Pathway
    T Cell Receptor Signaling Pathway
  • Common G-Chain signaling pathway
    Common G-Chain signaling pathway
  • IL1 signaling pathway
    IL1 signaling pathway
  • IL17 signaling pathway
    IL17 signaling pathway
  • Kolb RH, Greer PM, Cao PT, Cowan KH, Yan Y. ERK1/2 Signaling Plays an Important Role in Topoisomerase II Poison-Induced G2/M Checkpoint Activation. Tan M, ed. PLoS ONE. 2012;7(11):e50281.
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