CD134 antigens

CD134 antigens general information

CD134 Gene ID 22163
CD134 Official Full Name tumor necrosis factor receptor superfamily, member 4
CD134 Alias OX-40, TNFRSF4
CD134 Cellular Expression T
CD134 Ligand/Receptor/Association CD134 ligand
CD134 Function T-cell activation, proliferation and differentiation, apoptosis and cell adhesion
CD134 Summary Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting na?ve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels.

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.