CD antigens related to MAPK-Erk Pathway

CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.

Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.

CD antigens chart related to MAPK-Erk Pathway

Name Name in pathway Alias Function
CD3e T3E T3E, TCRE, CD3 epsilon T-cell activation signaling and regulation of TCR expression
CD11a Integrins LFA-1, LFA1A, ITGAL Intracellular adhesion and costimulation.
CD11c Integrins p150,95, CR4, integrin αX, LFA-1A, ITGAX Cell adhesion
CD18 Integrins Integrin β2, ITGB2, MFI7 Adhesion, cell signaling
CD29 Integrins Integrin β1, ITGB1, FNRB Lymphocyte and endothelial adhesion, lymphocyte trafficking and transvascular migration
CD41 Integrins ITGA2B Platelet activation and aggregation.
CD49b Integrins VLA-2, ITGA2 Adhesion and platelet aggregation.
CD49c Integrins VLA-3, ITGA3 Adhesion and signal transduction
CD49e Integrins VLA-5, ITGA5 Adhesion, regulation of cell survival and apoptosis
CD49f Integrins VLA-6, ITGA6 Embryogenesis, adhesion and cell migration
CD51 Integrins Vitronectin receptor, ITGAV, MSK8 Adhesion and signal transduction
CD61 Integrins GPIIIa, ITGB3, GP3A Cell adhesion
CD82 KAI1 R2, KAI1, Tetraspanin-27 Signal transduction
CD98 SLC3A2 4F2hc, SLC3A2, MDU1 Cell activation and cell aggregation
CD103 Integrins HUMINAE, ITGA1 Lymphocyte retention. Receptor for E-cadherin.
CD120a TNFRSF1A TNFR-I, TNFRSF1A, TNFR1 Receptor for TNF
CD120b TNFRSF1B TNFR-II, TNFRSF1B, TNFR2 Receptor for TNF. Involved in cell differentiation, apoptosis and necrosis
CD154 CD40L CD40L, CD40 Ligand, gp39, TRAP Mediates B-cell proliferation, IgE production and is involved in immunoglobulin class switching
CD242 Integrins ICAM-4 Ligand for the leukocyte adhesion protein LFA-1
CD261 TNFRSF10A TRAIL-R1, DR4, TNFRSF10A Induces apoptosis, promotes activation of NFkB