CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.
Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.
|Name||Name in pathway||Alias||Function|
|CD95||Fas||Apo-1, FASLG, APTL, TNFRSF6||Induces apoptosis|
|CD120a||TNFR1||TNFR-I, TNFRSF1A, TNFR1||Receptor for TNF|
|CD178||FASL||FasL, CD95L, FASLG, Fas Ligand||T-cell mediated cytotoxicity|
|CD253||TRAIL||TRAIL, Apo-2L, TL2, TNFSF10||Induces cell death by apoptosis|
|CD261||DR4||TRAIL-R1, DR4, TNFRSF10A||Induces apoptosis, promotes activation of NFkB|
|CD262||DR5||TRAIL-R2, DR5, TNFRSF10B||Activated by TNFSF10 / TRAIL and transduces apoptosis signal|
|CD264||DcR2||DCR2, TRAIL-R4, TNFRSF10D||Receptor for TRAIL, inhibits apoptosis|
|CD271||P75||NGFR, p75 (NTR)||Regulates neuronal growth, migration, differentiation and cell death during stem cells.|
|CD358||DR6||TNFRSF21||May activate NFkB and promote apoptosis. May activate JNK and be lymphocytes. involved in T-cell differentiation. Required for both normal cell body death and axonal pruning|