VAV1 Antibodies, cDNA Clones Research Reagents

All VAV1 reagents are produced in house and quality controlled, including 1 VAV1 Antibody, 1 VAV1 Gene. All VAV1 reagents are ready to use.

VAV1 Antibody (1)

    VAV1 cDNA Clone (1)


    In expression vector

    VAV1 Background

    VAV1, short for vav guanine nucleotide exchange factor 1, is normally expressed exclusively in the hematopoietic system, where it functions as a specific GDP/GTP nucleotide exchange factor (GEF), strictly regulated by tyrosine phosphorylation. Vav1 contains many characteristic structural motifs important for its function as a versatile signal transducer. In hematopoietic cells, Vav1 is phosphorylated following cell surface receptor activation, triggering re-organization of the cytoskeleton and regulation of other cellular functions including transcription, cytokine production, cell cycle progression, and Ca(2+) mobilization.

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