VAV1 Antibodies, cDNA Clones Research Reagents

All VAV1 reagents are produced in house and quality controlled, including 1 VAV1 Antibody, 1 VAV1 Gene. All VAV1 reagents are ready to use.

VAV1 Antibody (1)

    VAV1 cDNA Clone (1)

    NM_005428.3

    In expression vector

    VAV1 Background

    VAV1, short for vav guanine nucleotide exchange factor 1, is normally expressed exclusively in the hematopoietic system, where it functions as a specific GDP/GTP nucleotide exchange factor (GEF), strictly regulated by tyrosine phosphorylation. Vav1 contains many characteristic structural motifs important for its function as a versatile signal transducer. In hematopoietic cells, Vav1 is phosphorylated following cell surface receptor activation, triggering re-organization of the cytoskeleton and regulation of other cellular functions including transcription, cytokine production, cell cycle progression, and Ca(2+) mobilization.

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