Catalogue | Product name | Purity | Endotoxin |
10804-H08H1 | Human TGFB1 (LAP) / TGF-beta 1 Protein (His Tag) |
> 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
10804-HNAC | Human / Rhesus / Canine TGF-beta 1 / TGFB1 Protein |
> 95 % as determined by HPLC | < 1.0 EU / μg protein |
80116-RNAH | Rat / Mouse TGF-beta 1 / TGFB1 Protein | > 90 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
90294-C08H | Cynomolgus TGF-beta 1 / TGFB1 Protein (His Tag) |
> 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
50976-M08H | Mouse NBL1 / DAND1 / DAN Protein (His Tag) |
> 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
80021-R02H | Rat GFRA1 / GFR alpha-1 Protein (Fc Tag) | > 90 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
10214-H01H | Human BMP-5 Protein (Fc Tag) | > 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
51127-M08H | Mouse FSTL1 Protein (His Tag) | > 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
10267-H02H | Human Noggin / NOG Protein (Fc Tag) | > 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
10804-H08H | Human Latent TGF-beta 1 / TGFB1 Protein (His Tag) |
> 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
80116-R08H | Rat Latent TGF-beta 1 / TGFB1 Protein (His Tag) |
> 90 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
50727-M20B | Mouse Smad2 Protein (His & GST Tag) | > 90 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
13968-H08H | Human ROR1 Protein (ECD, His Tag) | > 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
80399-R08H | Rat NCAM1 / CD56 Protein (His Tag) | > 95 % as determined by SDS-PAGE | < 1.0 EU / μg protein |
TGF-beta (Transforming growth factor beta / TGF-β) is a type of cytokine. It is comprised of a large group of proteins, including the activin/inhibin family, bone morphogenetic proteins (BMPs), growth differentiation factors (GDFs), the TGF-beta subfamily, and glial cell line-derived neurotrophic factor (GDNF) family. TGF-beta superfamily proteins have been discovered in a variety of species, including invertebrates as well as vertebrates. TGF-beta superfamily members play fundamental roles in the regulation of various biological processes such as growth, development, tissue homeostasis and regulation of the immune system. TGF-beta superfamily of cytokines bind to receptors at the cell surface, and recruit two type I receptors and two type II receptors forming a tetrameric complex. Activated TGF-beta superfamily receptors induce a series of phosphorylation cascade, from receptor phosphorylation to subsequent phosphorylation and activation of downstream signal transducer R-Smads (receptor-activated Smads).