SUV39H1 Antibodies, cDNA Clones Research Reagents

All SUV39H1 reagents are produced in house and quality controlled, including 1 SUV39H1 Antibody, 31 SUV39H1 Gene, 1 SUV39H1 qPCR. All SUV39H1 reagents are ready to use.

SUV39H1 Antibody (1)

    SUV39H1 cDNA Clone (31)


    In cloning vector

    SUV39H1 qPCR Primer (1)

    SUV39H1 Background

    SUV39H1, the histone methyltransferase (HMTase) of histone H3 lysine 9 trimethylation (H3K9me3), is a known transcriptional repressor of inflammatory genes. SUV39H1 as an oncogene in melanoma and underscore the role of chromatin factors in regulating tumorigenesis. The ability of mycobacteria to form biofilms, a survival strategy of the bacteria dependent upon cell-cell adhesion, was dramatically reduced in the presence of SUV39H1. Thus, this novel defense mechanism against mycobacteria represents a surrogate function of the epigenetic modulator, SUV39H1, and operates by interfering with their cell-cell adhesion ability. Overexpression of SUV39H1 may reduce renal inflammation and apoptosis via epigenetic modulation, thus plays a protective role in DN.

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