SOCS4 Antibodies, cDNA Clones Research Reagents

All SOCS4 reagents are produced in house and quality controlled, including 1 SOCS4 Antibody, 15 SOCS4 Gene, 1 SOCS4 qPCR. All SOCS4 reagents are ready to use.

SOCS4 Antibody (1)

    SOCS4 cDNA Clone (15)

    SOCS4 qPCR Primer (1)

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    SOCS4 Background

    Suppressor of cytokine signaling (SOCS) proteins are key regulators of innate and adaptive immunity. Mice lacking functional SOCS4 are hypersusceptible to primary infection with influenza A virus (IAV), displaying dysregulated pro-inflammatory cytokine and chemokine production in the lungs, delayed viral clearance and impaired trafficking of influenza-specific CD8(+) T cells to the site of infection. SOCS4 is a known inhibitor of epidermal growth factor (EGF) receptor signalling, and functional studies demonstrated specific upregulation of EGF-dependent immune stimulation in affected family members.

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