SIRT6 Antibodies, cDNA Clones Research Reagents

All SIRT6 reagents are produced in house and quality controlled, including 2 SIRT6 Antibody, 16 SIRT6 Gene, 1 SIRT6 IP Kit, 1 SIRT6 qPCR. All SIRT6 reagents are ready to use.
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All SIRT6 Reagents

SIRT6 General Information

SIRT6 Antibody (2)

Application:
Clonality:
Host:

    SIRT6 cDNA Clone (16)

    NM_001031649.1

    In expression vector

    untagged

    SIRT6 qPCR Primer (1)

    SIRT6 IP Kit (1)

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    SIRT6 Background

    Sirtuin 6 (SIRT6) is a nicotinamide adenine dinucleotide(+) (NAD(+)) dependent enzyme and stress response protein. SIRT6 has several different functions in multiple different molecular pathways related to DNA repair, glycolysis, gluconeogenesis, tumorigenesis, neurodegeneration, cardiac hypertrophic responses, and more. SIRT6 is a main regulator of metabolism and lifespan and its importance has been implicated in the prevention against aging-related diseases. SIRT6 depletion enhanced chemosensitivity of human hepatoma cells by downregulating MDR1 expression through suppressing C/EBPbeta. SIRT6 may serve as a novel target to enhance chemosensitivity in HCC cells.

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