SILV Antibodies, cDNA Clones Research Reagents

All SILV reagents are produced in house and quality controlled, including 1 SILV Antibody, 26 SILV Gene, 1 SILV qPCR. All SILV reagents are ready to use.

SILV Antibody (1)

    SILV cDNA Clone (26)


    SILV qPCR Primer (1)

    SILV Background

    SILV gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

    SILV References

    • Eich C, Lasonder E, Cruz LJ, et al. Proteome Based Construction of the Lymphocyte Function-Associated Antigen 1 (LFA-1) Interactome in Human Dendritic Cells. Mattei F, ed. PLoS ONE. 2016;11(2):e0149637.

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