RELT/TNFRSF19L Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All RELT/TNFRSF19L reagents are produced in house and quality controlled, including 5 RELT/TNFRSF19L Antibody, 1 RELT/TNFRSF19L ELISA, 39 RELT/TNFRSF19L Gene, 2 RELT/TNFRSF19L Lysate, 2 RELT/TNFRSF19L Protein, 2 RELT/TNFRSF19L qPCR. All RELT/TNFRSF19L reagents are ready to use.

RELT/TNFRSF19L Protein (2)

    RELT/TNFRSF19L Antibody (5)

      RELT/TNFRSF19L ELISA Kit & Match Antibody ELISA Pair Set (1)

      RELT/TNFRSF19L cDNA Clone (39)

      NM_032871.3
      NM_177073.6
      NM_001108495.1

      RELT/TNFRSF19L Lysate (2)

        RELT/TNFRSF19L Background

        Receptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. RELT/TNFRSF19L is a type I transmembrane glycoprotein with a cysteine-rich extracellular domain, possessing significant homology to other members of the TNFR superfamily, especially TNFRSF19, DR3, OX4, and LTbeta receptor. RELT/TNFRSF19L is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. RELT/TNFRSF19L is able to activate the NF-κB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. Although the soluble form of RELT fusion protein does not inhibit the one-way mixed lymphocyte reaction, immobilized RELT/TNFRSF19L is capable of costimulating T-cell proliferation in the presence of CD3 signaling.

        RELT/TNFRSF19L References

        • Sica GL, et al. (2001) RELT, a new member of the tumor necrosis factor receptor superfamily, is selectively expressed in hematopoietic tissues and activates transcription factor NF-kappaB. Blood. 97(9): 2702-7.
        • Polek TC, et al. (2006) The TNF receptor, RELT, binds SPAK and uses it to mediate p38 and JNK activation. Biochem Biophys Res Commun. 343(1): 125-34.
        • Cusick JK, et al. (2006) Identification of RELT homologues that associate with RELT and are phosphorylated by OSR1. Biochem Biophys Res Commun. 340(2): 535-43.

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