PRNP/Prion Protein Proteins, Antibodies, cDNA Clones Research Reagents

PRNP (Prion Protein) is a protein coding gene located on human chromosome 20p13. PRNP is also known as CJD, GSS, PrP, ASCR, KURU, PRIP, PrPc, CD230, AltPrP, p27-30, PrP27-30 and PrP33-35C. The human PRNP gene encodes an 8691 Da protein containing 73 amino acids. Ubiquitous expression in brain (RPKM 148.7), ovary (RPKM 52.6) and 24 other tissues Among its related pathways are Neuroscience and RET signaling. PRNP is related to identical protein binding and chaperone binding. PRNP is associated with some diseases, including Creutzfeldt-Jakob Disease and Fatal Familial Insomnia.

PRNP/Prion Protein Protein (1)

    PRNP/Prion Protein Antibody (1)

      PRNP/Prion Protein cDNA Clone (52)

      NM_000311
      NM_011170.2
      NM_012631.2
      NM_001047152.1

      PRNP/Prion Protein Lysate (1)

        PRNP/Prion Protein Background

        Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamental in the pathogenesis of transmissible spongiform encephalopathies. Generally, PRNP gene is associated with prion diseases, whereas variants of the PRNP gene may also explain some cases of Alzheimer disease (AD) and frontotemporal dementia (FTD) in Caucasian populations.

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