NKp30/NCR3 Proteins, Antibodies, cDNA Clones Research Reagents

All NKp30/NCR3 reagents are produced in house and quality controlled, including 4 NKp30/NCR3 Antibody, 4 NKp30/NCR3 Gene, 5 NKp30/NCR3 Lysate, 5 NKp30/NCR3 Protein, 1 NKp30/NCR3 qPCR. All NKp30/NCR3 reagents are ready to use.

NKp30/NCR3 Protein (5)

    NKp30/NCR3 Antibody (4)

      NKp30/NCR3 cDNA Clone (4)


      In expression vector

      In lentiviral vector


      In cloning vector


      In cloning vector

      NKp30/NCR3 qPCR Primer (1)

      NKp30/NCR3 Lysate (5)

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        NKp30/NCR3 Background

        Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp3, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp3 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp3 was recently reported. NKp3 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp3 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp3 is a stimulatory receptor on human NK cells implicated in tumor immunity, and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.

        NKp30/NCR3 References

        • Warren HS, et al. (2005) Evidence that the cellular ligand for the human NK cell activation receptor NKp30 is not a heparan sulfate glycosaminoglycan. J Immunol. 175(1): 207-12.
        • Mulcahy H, et al. (2006) LST1 and NCR3 expression in autoimmune inflammation and in response to IFN-gamma, LPS and microbial infection. Immunogenetics. 57(12): 893-903.
        • Hsieh CL, et al. (2006) NKp30 is a functional activation receptor on a subset of rat natural killer cells. Eur J Immunol. 36(8): 2170-80.
        • Ponnampalam AP, et al. (2008) Identification and hormonal regulation of a novel form of NKp30 in human endometrial epithelium. Eur J Immunol. 38(1): 216-26.

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