NCL Antibodies, cDNA Clones Research Reagents

All NCL reagents are produced in house and quality controlled, including 1 NCL Antibody, 31 NCL Gene. All NCL reagents are ready to use.

NCL Antibody (1)

    NCL cDNA Clone (31)

    NM_012749.2

    In cloning vector

    In lentiviral vector

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    NCL Background

    Nucleolin (NCL) is a multifunctional protein that mainly localized in the nucleolus, it is also found in the nucleoplasm, cytoplasm and cell membrane. The three main structural domains allow the interaction of NCL with different proteins and RNA sequences. Moreover, specific post-translational modifications and its shuttling property also contribute to its multifunctionality. NCL has been demonstrated to be involved in a variety of aspects such as ribosome biogenesis, chromatin organization and stability, DNA and RNA metabolism, cytokinesis, cell proliferation, angiogenesis, apoptosis regulation, stress response and microRNA processing. NCL has been increasingly implicated in several pathological processes, especially in tumorigenesis and viral infection, which makes NCL a potential target for the development of anti-tumor and anti-viral strategies.

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