MKK7 Antibodies Research Reagents

MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7) is a protein coding gene located on human chromosome 19p13.2. MAP2K7 is also known as MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4 and SAPKK-4. The human MAP2K7 gene encodes a 47485 Da protein containing 419 amino acids. The MAP2K7 protein is ubiquitously expressed in testis, spleen and other tissues. Among its related pathways are GDNF-Family Ligands and Receptor Interactions and Integrin Pathway. MAP2K7 is related to transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. MAP2K4 is an important paralog of MAP2K7 gene. MAP2K7 is associated with some diseases, including Acneiform Dermatitis and Colorectal Adenocarcinoma.

MKK7 Antibody (2)

    MKK7 Background

    Map2k7 haploinsufficiency causes a distinctive pattern of cognitive impairment strongly suggestive of an inability to sustain attention, in accordance with those seen in psychiatric patients carrying out similar tasks. This may be important for understanding the mechanisms of cognitive dysfunction in clinical populations.

    Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.